Organic molecule-based photothermal agents: an expanding photothermal therapy universe

Recent advances in the development of organic photothermal nano-agents

A review of organic nanomaterials in photothermal cancer therapy

Photothermal therapy has inspired numerous interests due to its minimal invasion, easy to perform, and possibilities to treat embedded tumors in vital regions. In this review, examples where various types of photothermal nanoagents including carbon-based, organic near-infrared dye-based, polymer-based nanomaterials have been utilized to converse near-infrared light energy to heating within tumo...

Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells.

Copper sulphides, as a novel kind of photothermal agent for photothermal therapy (PTT) of cancer cells, have attracted increasing attention in recent years due to good photostability, synthetic simplicity, low toxicity and low cost. However, the unsatisfactory photothermal conversion efficiency of copper sulphides limits their bioapplication as PTT agents. Herein, Cu7.2S4 NCs with a mean size o...

Fractionated photothermal antitumor therapy with multidye nanoparticles

PURPOSE Photothermal therapy is an emerging cancer treatment paradigm which involves highly localized heating and killing of tumor cells, due to the presence of nanomaterials that can strongly absorb near-infrared (NIR) light. In addition to having deep penetration depths in tissue, NIR light is innocuous to normal cells. Little is known currently about the fate of nanomaterials post phototherm...

Protein-based photothermal theranostics for imaging-guided cancer therapy.

The development of imageable photothermal theranostics has attracted considerable attention for imaging guided photothermal therapy (PTT) with high tumor ablation accuracy. In this study, we strategically constructed a near-infrared (NIR) cyanine dye by introducing a rigid cyclohexenyl ring to the heptamethine chain to obtain a heptamethine dye CySCOOH with high fluorescence intensity and good ...